Discovering The Right Injectable: Profhilo vs Polynucleotides
Posted on 1st August 2025 by Olivia
If you’ve ever searched for Profhilo vs Polynucleotides for skin rejuvenation, you’re already on the path to radiant skin. Both treatments offer unique hydration and regenerative results, and today, you’ll learn how to choose the best fit for your complexion at Dr Yusra Clinic.
What Does Profhilo Do for Your Face?
Profhilo is a purity‑boosting injectable made from ultra‑high and low molecular weight hyaluronic acid. It disperses beneath the skin using a standardized 5‑point injection technique on each side of the face. The result? Intense hydration, a lifted appearance, improved firmness, and a radiant glow, without adding volume or altering facial contours.
Clients often notice skin improvement within days. Complete effects emerge over 4-6 weeks, and results typically last 6 to 12 months.
What Do Polynucleotides Do to the Skin?
Polynucleotides consist of purified chains of nucleotides, derivatives of salmon DNA, that stimulate fibroblasts, encouraging deep collagen and elastin formation. This cellular repair pathway reduces inflammation, enhances skin hydration, and supports antioxidant protection.
Unlike immediate hydration, polynucleotides deliver gradual yet transformative regeneration. Improvements in texture and elasticity emerge after a few treatments, with benefits lasting up to 12 months or more.
Is Profhilo Better than anti-wrinkle treatments?
Profhilo is not a filler and isn’t intended to smooth dynamic wrinkles like anti-wrinkle treatments. Instead, it enhances skin moisture, tightness, elasticity, and overall glow, making it complementary rather than competitive to anti-wrinkle treatments. It’s ideal for clients seeking natural radiance and skin quality, rather than freeze results or volume build‑up.
Profhilo works in harmony with botulinum toxin and can be used as part of a combined aesthetic plan for a fresher, hydrated complexion.
What is Profhilo and How Long Does It Last?
Profhilo offers a two‑session protocol: one injection, then another 4 weeks later. Results evolve over a month and maintain themselves for around six months. Many opt to repeat treatment twice per year to preserve youthful hydration and skin tightness.
Results completion time: ~4-6 weeks. Duration: ~6-12 months. Downtime is minimal, a few hours of mild swelling or redness in most cases.
What is the Difference Between Polynucleotides and Profhilo?
Which Should You Choose: Polynucleotides or Profhilo?
If you’re craving immediate hydration, plumpness, and luminosity, Profhilo skin tightening treatment may be ideal. It’s fast, effective, and delivers visible glow with minimal fuss.
But if your skin needs deep repair, a legacy of scarring, inflammation, pigmentation, or dryness, polynucleotides skin rejuvenation could be superior. This treatment orchestrates tissue renewal from within, offering cumulative, long‑lasting benefits,
For some patients, a combined approach is recommended: Begin with Profhilo to hydrate and firm, then use polynucleotides to regenerate and stabilise. This layered strategy often yields the most prominent skin‑enhancing results.
Local Availability: Polynucleotides & Profhilo Near Me
At Dr Yusra Clinic, clinics in Manchester, London, and Liverpool offer both treatments. Whether you search for “Profhilo near me” or “polynucleotides treatment near me Manchester”, you can access these cutting‑edge injectables and book a bespoke consultation at a convenient location.
Every treatment plan is individually tailored, whether you seek firmness, hydration, texture refinement, or anti‑inflammatory skin healing.
Treatment Protocols: Sessions & Longevity
- Profhilo: 2 sessions, spaced 4 weeks apart, followed by maintenance every 6–12 months. Hydration is visible almost immediately.
- Polynucleotides: Typically 3-4 sessions, spaced 2-3 weeks apart. Results begin around 7–10 days and evolve over several weeks. Maintenance advised every 9-18 months depending on skin status
Why Choose Dr Yusra Clinic for These Treatments?
- Award‑Winning Aesthetic Expertise: Led by Dr Yusra Al‑Mukhtar, multiple awards for practitioner excellence and induction into the Aesthetic Medicine Wall of Fame.
- Dedicated Clinics in Manchester, London & Liverpool, combining luxury boutique settings with medically supervised protocols.
- Precision Customisation: Treatments tailored to skin type, age (35‑75 target), and individual concerns, maximising results with minimal discomfort.
- Integration with Other Therapies: Combine injectables with collagen‑stimulating skincare, microneedling, or chemical peels for synergistic benefits.
Ready to Rejuvenate? Let’s Find Your Perfect Treatment
Whether you’re looking to deeply hydrate your skin with Profhilo, repair it at a cellular level with Polynucleotides, or combine both for enhanced results,our expert team at Dr Yusra Clinic is here to guide you.
With clinics in Manchester, London, and Liverpool, it’s never been easier to explore award-winning, injectable skin rejuvenation treatments close to home.
✨ Book your consultation today and discover whether Profhilo or Polynucleotides is right for your skin goals.
👉 Click here to get started and let us help you glow from within—with results that are subtle, natural, and entirely you.
FAQs
1. How long do Profhilo results last?
Two treatment sessions spaced one month apart produce visible hydration and firmness that lasts around 6-12 months. Maintenance every 6-12 months is recommended.
2. How long do polynucleotide treatments last?
Results typically last between 12 and 18 months after a full course of 3-4 sessions. Maintenance is advised every 9-12 months depending on individual skin health.
3. What are the main differences between polynucleotides and Profhilo?
Profhilo delivers fast hydration and some collagen stimulation via hyaluronic acid. Polynucleotides act deeper: they repair tissue, reduce inflammation, and regenerate skin quality over time.
4. Are these treatments safe?
Both treatments are well tolerated. Side effects may include minor swelling or redness. Polynucleotides derive from salmon DNA; individuals with fish allergy should consult first. Research is promising but still emerging.
5. Can I combine Profhilo and polynucleotides?
Absolutely. A combined protocol can offer the immediate radiance of Profhilo along with the long-term repair of polynucleotides,especially beneficial for ageing or compromised skin.
Award‑Winning Aesthetic Excellence
Dr Yusra Al‑Mukhtar has been recognised as the Best Medical Aesthetic Practitioner of the Year for three consecutive years; a prestigious honour awarded based on exceptional clinical expertise, patient outcomes, safety standards, and dedication to aesthetic excellence. She is also the first medical practitioner to be inducted into the Aesthetic Medicine Wall of Fame, a landmark achievement that reflects her leadership and influence in the field of aesthetic medicine in the UK and internationally.
At Dr Yusra Clinic, we are equally proud to be named Best Aesthetic Clinic in the North of England and Best Clinical Team, both three times, acknowledging our commitment to the highest standards of patient care, medical ethics, and outstanding treatment results. These industry‑leading awards recognise our team’s collective dedication to delivering safe, personalised, and science‑led aesthetic treatments that help our patients look and feel their best.
If you are searching for an award‑winning aesthetic clinic known for natural results, advanced techniques, and patient‑centered care, you are in expert hands with Dr Yusra Clinic.
