The Science Behind NAD⁺ Therapy and Cellular Repair

Ageing begins at the cellular level. Every second, the body’s trillions of cells are repairing, renewing, and regenerating – yet as we grow older, these essential processes begin to slow. Why? A major reason lies in declining levels of NAD⁺ (nicotinamide adenine dinucleotide) – a coenzyme that powers nearly every biological function.

At Dr Yusra Clinic – with award-winning locations in Liverpool, Manchester, and London – we explore the science of longevity and cellular repair to help our patients age gracefully. NAD⁺ therapy sits at the forefront of regenerative aesthetics, supporting energy metabolism, DNA repair, and skin health from within.

What Is NAD⁺ and Why Is It Important?

NAD⁺ is a molecule found in every living cell. It acts as a critical coenzyme in metabolic reactions, converting nutrients into energy and facilitating communication between the cell nucleus and mitochondria – the energy powerhouses of our cells.

In its simplest form, NAD⁺ is a molecular currency that allows the body to repair DNA, regulate immunity, and maintain youthful cell function. Without it, cellular systems weaken, and ageing accelerates.

From around age 30, NAD⁺ levels naturally decline, reducing the body’s capacity to repair damage caused by stress, pollution, UV exposure, and toxins. Restoring these levels supports improved vitality, cognition, and skin quality.

The Science of Cellular Repair and NAD⁺

Every day, our cells face oxidative stress, inflammation, and environmental damage. These processes break down DNA and weaken the skin’s structural proteins, leading to visible signs of ageing such as dullness, wrinkles, and reduced elasticity.

Sirtuins and Longevity Pathways

One of NAD⁺’s most fascinating roles is its relationship with sirtuins – a family of seven enzymes (SIRT1–SIRT7) known as “longevity proteins.”
Sirtuins rely entirely on NAD⁺ to function. When NAD⁺ binds to these enzymes, it activates processes that enhance DNA stability, regulate inflammation, and promote cellular renewal.

This relationship forms part of the body’s natural defence against premature ageing, explaining why maintaining NAD⁺ levels can significantly improve resilience and repair at a cellular level.

Mitochondrial Function and Energy Production

NAD⁺ is also vital for mitochondrial efficiency – the process by which cells generate ATP (adenosine triphosphate), the body’s main energy molecule.
With abundant NAD⁺, mitochondria produce energy more effectively, keeping cells healthy and active. When NAD⁺ levels drop, so too does cellular energy, resulting in fatigue, slower recovery, and visible skin ageing.

Together, sirtuin activation and mitochondrial repair form the foundation of cellular longevity – the science that underpins NAD⁺ therapy at Dr Yusra Clinic.

Why NAD⁺ Levels Decline Over Time

Several factors accelerate NAD⁺ depletion beyond natural ageing:

• Chronic stress and inflammation
  
• Excess alcohol or a poor diet
  
• Sleep deprivation and circadian disruption
  
• UV radiation and environmental toxins
  

As NAD⁺ falls, the body’s ability to protect DNA and repair tissue diminishes. This manifests as dull skin, reduced energy, slower metabolism, and increased susceptibility to disease.

How to Naturally Support NAD⁺ Levels

While lifestyle and nutrition play a vital role in maintaining cellular health, a scientifically guided approach can further optimise NAD⁺ levels and support long-term wellbeing.

Foods rich in vitamin B3 (niacin), tryptophan, and other essential nutrients contribute to natural NAD⁺ synthesis, while regular exercise, restorative sleep, and stress management help preserve the body’s ability to generate and recycle NAD⁺ efficiently.

At Dr Yusra Clinic, we take a comprehensive approach to cellular optimisation, combining medical insight with tailored wellness strategies that help maintain balanced NAD⁺ activity as part of a wider regenerative and longevity programme.

The Benefits of NAD⁺ Therapy for Cellular Health

Patients often describe the effects of NAD⁺ therapy as a “deep recharge” for their body and mind. By restoring the cell’s natural ability to create energy, NAD⁺ therapy helps:

• Boost cellular energy and performance
  
• Enhance skin quality and elasticity
  
• Support cognitive clarity and focus
  
• Accelerate tissue recovery after stress or injury
  
• Promote balanced ageing from the inside out
  

NAD⁺ and Ageing Gracefully

Healthy ageing is not about reversing time but supporting the body’s intrinsic repair systems. NAD⁺ therapy encourages these natural mechanisms to function at their peak – helping skin look brighter, muscles recover faster, and energy remain stable throughout the day.

In regenerative aesthetics, NAD⁺ complements treatments such as polynucleotides, exosomes, and skin boosters, each designed to strengthen the skin’s cellular matrix and improve overall vitality.

If you’re exploring cellular repair treatments to maintain youthfulness and wellbeing, NAD⁺ therapy offers a scientifically backed foundation for longevity and beauty.

The Future of Regenerative Aesthetics and NAD⁺ Science

Research into NAD⁺ continues to uncover new applications for metabolic and aesthetic health. Scientists now understand that enhancing NAD⁺ levels influences key longevity pathways, including sirtuin activation, DNA repair, and mitochondrial biogenesis.

In the aesthetics field, Dr Yusra Clinic remains at the forefront of regenerative medicine – integrating NAD⁺-focused cellular treatments alongside advanced technologies such as polynucleotides, microneedling, and Ultracel skin tightening to help patients achieve glowing, resilient skin at every age.

Whether you’re looking to restore radiance, combat fatigue, or support overall skin rejuvenation, NAD⁺ therapy represents a pioneering step in age management that works in harmony with your biology.

Final Thoughts – Repair, Regenerate, Renew

Every cell in your body has the potential to repair itself – it simply needs the right biochemical tools. By replenishing NAD⁺, we provide those tools, re-energising cellular processes and promoting a healthier, more youthful complexion.

At Dr Yusra Clinic, we believe that beauty begins with biology. Our medically led approach combines science, safety, and artistry to deliver results that help you look and feel your best at every stage of life.

Whether you’re based in Liverpool, Manchester, or London, our medical team welcomes you to experience NAD⁺ therapy as part of a holistic regenerative journey. Book your consultation at your nearest Dr Yusra Clinic location today.

Frequently Asked Questions

1. What does NAD⁺ therapy do?

NAD⁺ therapy supports the body’s cellular repair systems, helping to restore energy, protect DNA, and promote youthful cell function.

2. Can NAD⁺ help with visible ageing?

Yes. By improving mitochondrial efficiency and stimulating DNA repair, NAD⁺ therapy can enhance skin texture, elasticity, and glow.

3. How long do the benefits of NAD⁺ therapy last?

Results vary, but improved energy, focus, and skin health are often noticed within weeks and maintained with regular treatment.

4. Is NAD⁺ therapy safe?

When administered under medical supervision, NAD⁺ therapy is considered very safe. At Dr Yusra Clinic, all treatments are performed by qualified clinicians.

5. How does NAD⁺ therapy fit with other treatments?

NAD⁺ works synergistically with regenerative options such as polynucleotides, microneedling, and Ultracel to enhance overall results.

Award-Winning Aesthetic Excellence

Dr Yusra Al-Mukhtar has been recognised as the Best Medical Aesthetic Practitioner of the Year for three consecutive years, a prestigious honour based on exceptional clinical expertise, safety standards, and dedication to aesthetic excellence.
She is also the first medical practitioner inducted into the Aesthetic Medicine Wall of Fame, reflecting her leadership in the UK and globally.

Dr Yusra Clinic has been named Best Aesthetic Clinic in the North of England and Best Clinical Team, both three times – achievements that reflect our unwavering commitment to patient care and natural, science-led results.

If you are searching for an award-winning aesthetic clinic known for natural outcomes, advanced techniques, and compassionate expertise, you are in expert hands with Dr Yusra Clinic.